4 doctors weighed in:

How does imodium (loperamide) actually work, anyway? How bad can it be to overdose?

4 doctors weighed in
Garrett Caldwell
Family Medicine
3 doctors agree

In brief: Imodium (loperamide)

Imodium anti-diarrheals are actually a drug called loperamide.
This drug acts on the walls of the gut inhibiting their movement and increasing the tone in the sphincter muscle of your anus. This causes your feces to stop moving in your gut allowing your body to absorb more of the water. The drug is fairly safe, however large overdosing can cause constipation, paralytic ileus or toxic megacolon.

In brief: Imodium (loperamide)

Imodium anti-diarrheals are actually a drug called loperamide.
This drug acts on the walls of the gut inhibiting their movement and increasing the tone in the sphincter muscle of your anus. This causes your feces to stop moving in your gut allowing your body to absorb more of the water. The drug is fairly safe, however large overdosing can cause constipation, paralytic ileus or toxic megacolon.
Garrett Caldwell
Garrett Caldwell
Answer assisted by Garrett Caldwell, Medical Student
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