5 doctors weighed in:

A carcinogenic mutation is not inheritable. What could be the reason for this?

5 doctors weighed in
Dr. Susan Wingo
Internal Medicine - Endocrinology
4 doctors agree

In brief: Location

Only mutations affecting the "germ line" - eggs in women, sperm-producing cells in men - can be passed on.
Mutations caused by radiation or other carcinogens that occur in the thyroid, (or any tissue outside the ovary/testis), can not be inherited, regardless of whether the mutation occurs early in fetal/embryologic development or as an older adult.

In brief: Location

Only mutations affecting the "germ line" - eggs in women, sperm-producing cells in men - can be passed on.
Mutations caused by radiation or other carcinogens that occur in the thyroid, (or any tissue outside the ovary/testis), can not be inherited, regardless of whether the mutation occurs early in fetal/embryologic development or as an older adult.
Dr. Susan Wingo
Dr. Susan Wingo
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