Does the brca2 gene also cause colon cancer? Or just breast and ovarian?

BRCA for breast. Brca genetic mutations are for breast and ovarian cancers, for for colonic cancers apc gene, & familial non polyposis gene mutation are tested. 75% of colon cancers has no family history, best way to detect early is by regular doctor visits and colonoscopic examinations for early detection and cure.
Not colon. There are genetic mutations associated with the development of colon cancer and a consultation with a genetic counselor would be indicated for people who have family histories of these cancers.

Related Questions

Mom died of colon cancer, all 4 of dad's sis had breast cancer or precancer. 1 of the sis tested negative for cancer gene. Do I have elevated risk?

Yes, you do. First, I'm sorry to hear about your mom. That's so hard. And it's hard to worry about your own risk. You do have a higher risk of cancer, and it is probably not due to the breast/ovarian cancer gene (brca). Lynch syndrome is more likely. I can't tell you your exact risk because that depends on the age of your mom and your aunts when they were diagnosed. Tell every doctor this history from now on!
Colon cancer risk. Unfortunately, colon cancer is very common in all segments of society (almost second most common cause of cancer death). There is a life time risk of about 1out of twenty five people developing colon tumors. Family history of colon cancer and other cancers in close family members and multiple generations greatly increases the risk in other family members developing colon cancer.
Family history of Ca. When many cases of cancer occur in a family, it is most often due to chance or because family members have been exposed to a common toxin, Less often, these cancers may be caused by an inherited gene mutation causing a family cancer syndrome. You should have baseline colonoscopy and mammogram by 40 and have regular surveillance.

My mother was diagnosed with breast cancer at 54, grandmother had pancreatic cancer at 70 and great aunt had colon cancer at 65. No one else has cancer in my large family. Could I have the brca gene?

Very Low Risk. The risk of having a brca mutation can be estimated at: http://www. Myriadpro. Com/brca-risk-calculator/calc. Html. A woman with ashkenazi jewish heritage and this family history would have about an 8% chance of having a brca mutation. Without ashkenazi heritage the risk drops to 1.5%. The best way to know for sure would be to have your mother see a genetic counselor and consider having testing.
Probably no. This test is most useful if there is more than one member of the family with breast cancer and or ovarian cancer. Furthermore this type of breast cancer ooccurs below the age of 45 years. So I do not think it would be useful for you to do this test......It is also quite expensive to do this test..
Not too likely but. If your mother's cancer was "triple negative" and if she's still alive (which I truly hope), she fulfills criteria for testing. Recently, pancreatic cancer was added to the criteria so if she can't or won't test, you should discuss this with your doc. Best to you.

How high of a risk do I have of getting uterine, ovarian, breast, and colon cancer if I have a strong history these and more on both sides of my fam?

You need BRAC and Co. Colaris gene testing and then u can get a better risk assessment so see your gyn as some gyns do this or your gyn can refer u to someone who does.
Family Hx of Cancer. It depends to a large extent on whether there are identifiable cancer genes in the family for each of these cancers. Your risk is definitely increased, but if you harbor the brca 1 or 2 genes, or there is a family history of fap or hnpcc, these risks rise considerably. Your doctor might want to explore the genetic history of the family, which can involve testing any living family members also.
Be seen. There are many variables that you could possess. Your physician can discuss your individual risk for these varied cancers.
Genetic counselor. A genetic counselor can get a more complete history from you and give you a more science based recommendation for you. Certainly you family history indicates you should follow up with your gynecologist and get routine pap smears annually.

My mom's paternal uncle had aml at 65 and his daughter had it at 53. My mom's father had colon cancer at 87 and she had breast cancer at 54. Genetic?

Cancer is common dis. Cancer is a disease of the genes yet most people get cancer unpredictably. Breast cancer does run in families more often than other cancers. So if your mother has had it, you are at some risk too...you should be alert and watchful. Learn to do a breast self examination once monthly...looking for any lumps and also get an annual clinical breast examination done by your doctor. Mammography comes lat.

My mother had lobular breast cancer at 54, her mother had pancreatic cancer at 71, and my great aunt had colon cancer at 65. Are these likely genetic?

Potentially. Breast cancer, pancreatic cancer, and colon cancer are three of a number of cancers that may be linked in families to specific genes. However, the vast majority of these three cancers are spontaneous (unrelated to inherited genetic traits). In your case, these are likely spontaneous, given the ages at disease presentation. A genetic counselor can help complete the picture and screen your family.
Genetic. Colon breast prostate cancer close familial genetic links and defined genes. You may want to seek services of genetic counselor. I am not aware of similar link to pancrease (pancrelipase) cancer.
Could be. Your family should speak with a genetic counselor.
Possibly. Breast cancer and pancreatic cancer are can be associated with a genetic component. Hope this helps.
Not really. There are malignant conditions wherein associations with various groups of tumors exist. This occurs in hereditary forms of breast and colon cancer and in conditions such as the Lynch Syndrome. In your situation the breast Ca is most likely associated with the MMTV virus, the colon cancer with the polyoma virus and pancreas cancer with an undefined oncogenic factor.

Do you know are colon cancer, breast cancer, and stomach cancer genetically related?

Depends on what you. It is hard to know what you mean. If you mean hereditary, they typically are not except about 5 to 10% of the time there is cancer of the same type in one of the first degree relatives. But cancer is a common disease which will likely affect one in 3 people during a life time.
They can be. Depends on the family history, the age of the patient, where the cancer is located, specifically colon cancer. Right sided colon cancers are more likely genetically related than left sided ones. Hope this helps.

My mom died from colon cancer so did her mom. My mom's sister died frm breast cancer and brother died from lung cancer. How likely am I to get cancer?

Varies. You should see a genetic counselor who can look at your family tree and give you a better idea. The most worrisome possibility from what you have described is so far would be lynch syndrome, in which calling cancer (and others) run in families. You should definitely get a colonoscopy if you've not done so yet. For more info www. Askyourgynecologist. Org.
Family history. The risks of cancer depend on whether there is an abnormal gene that is inherited or a family grouping not related to a specific gene. It would be important to look at the entire family tree and decide about genetic testing or other risk reduction measures.

Mammo 7 yrs ago showed microcalcifications 1 breast. 18 mon of followups benign no change. No mammo since Jan '10 re colon cancer tx. 7 PET/CT since 2012 w last one 10/13. All clear. Scared. Worry?

Resume mammo. You should resume mammo. Biopsy any suspecious lesions as indicaed. You should also continue colon cancer surveillance, such as colonoscopy, physical exam, and perphaps tumor marker. CT scan or PET-CT only optional as indicated. Do not worry, just follow the standard care procedure.
You should. Probably resume screening mammography this year...you haven't had a mammo since 2010. The PET/CT was last year.