6 doctors weighed in:

Is it possible to have a narcolepsy diagnosis in a patient who never had REM sleep during an mslt's naps?

6 doctors weighed in
Dr. Michelle Zetoony
Internal Medicine - Sleep Medicine
4 doctors agree

In brief: Yes

Other reasons may occur for no rem. If person with cataplexy they do not need this test for absolute diagnosis.
If patient on medications that suppress rem that could be another cause.

In brief: Yes

Other reasons may occur for no rem. If person with cataplexy they do not need this test for absolute diagnosis.
If patient on medications that suppress rem that could be another cause.
Dr. Michelle Zetoony
Dr. Michelle Zetoony
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Dr. Mark Patterson
Pediatrics

In brief: Maybe

The international classification of sleep disorders has specific criteria which must be met to diagnose someone with narcolepsy.
As part of these criteria, you need to have 2 or more episodes of sleep onset-rems during the mslt. However, if the spinal fluid level of hypocretin is low, you can also make the diagnosis. But, you can have excessive daytime sleepiness that is not narcolepsy.

In brief: Maybe

The international classification of sleep disorders has specific criteria which must be met to diagnose someone with narcolepsy.
As part of these criteria, you need to have 2 or more episodes of sleep onset-rems during the mslt. However, if the spinal fluid level of hypocretin is low, you can also make the diagnosis. But, you can have excessive daytime sleepiness that is not narcolepsy.
Dr. Mark Patterson
Dr. Mark Patterson
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