7 doctors weighed in:

In stage III colon cancer what is the significance of spread to 2 of 17 lymph nodes? What are lymph nodes?

7 doctors weighed in
Dr. Gregory Hines
Family Medicine
4 doctors agree

In brief: Significant

Cancers spread by either blood vessels or lymphatic pathways.
Lymph nodes are collections of tissue along the lymphatic pathways, and are common places for tumor particles to start to grow. Your oncologist can discuss it in detail as to other measures you need to take, such as chemotherapy, radiation, more surgery, or some combination of all of the above.

In brief: Significant

Cancers spread by either blood vessels or lymphatic pathways.
Lymph nodes are collections of tissue along the lymphatic pathways, and are common places for tumor particles to start to grow. Your oncologist can discuss it in detail as to other measures you need to take, such as chemotherapy, radiation, more surgery, or some combination of all of the above.
Dr. Gregory Hines
Dr. Gregory Hines
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1 comment
Dr. Eric Kaplan
Any lymph node involvement suggests advanced disease that should be treated with chemotherapy if the patient is a candidate. See a good medical oncologist and learn the risks and benefits of chemotherapy so you can make an informed decision
Dr. Hung Khong
Internal Medicine - Oncology
2 doctors agree

In brief: Higer stage

Colon cancer with lymph node involvement is considered a stage iii disease.
After surgery, adjuvant chemotherapy (for 6 months) is recommended for stage iii colon cancer in most patients. Lymph nodes (or "lymph glands") are part of the lymphatic system that drain fluid/debris back to the blood (vasular system). Lymph nodes may enlarge with infection or cancer.

In brief: Higer stage

Colon cancer with lymph node involvement is considered a stage iii disease.
After surgery, adjuvant chemotherapy (for 6 months) is recommended for stage iii colon cancer in most patients. Lymph nodes (or "lymph glands") are part of the lymphatic system that drain fluid/debris back to the blood (vasular system). Lymph nodes may enlarge with infection or cancer.
Dr. Hung Khong
Dr. Hung Khong
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Dr. Chakshu Gupta
Pathology
2 doctors agree

In brief: Significant

Lymph nodes are stations along vessels draining tissue fluid to the heart.
When cancers spread outside tissue of origin, they often go first to local draining nodes. If the margins are negative, chemo may lead to a good response.

In brief: Significant

Lymph nodes are stations along vessels draining tissue fluid to the heart.
When cancers spread outside tissue of origin, they often go first to local draining nodes. If the margins are negative, chemo may lead to a good response.
Dr. Chakshu Gupta
Dr. Chakshu Gupta
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