16 doctors weighed in:

I have a high psa count but no prostate cancer. Recently I found that taking ibiprophen for 2 weeks before a psa blood test lowers my psa count. Why?

16 doctors weighed in
Dr. Chakshu Gupta
Pathology
9 doctors agree

In brief: Inflammation

Psa can be elevated in conditions other than cancer. Anti-inflammatory drugs can lower psa by reducing inflammation.
Studies that reported lower risk of prostate cancer with asprin use have since been challenged on this basis.

In brief: Inflammation

Psa can be elevated in conditions other than cancer. Anti-inflammatory drugs can lower psa by reducing inflammation.
Studies that reported lower risk of prostate cancer with asprin use have since been challenged on this basis.
Dr. Chakshu Gupta
Dr. Chakshu Gupta
Thank
Dr. Bahman Daneshfar
Radiation Oncology
3 doctors agree

In brief: Inflammation

Many reasons besides cancer can raise the psa.
Inflammation, infection, prostate stones, stimulation with rectal message or sex could elevate the psa to some degree, but not extremely high levels. Depending on your age and level of elevation one needs to make sure infection has been iliminated and if psa persists or keeps rising rebiopsy is needed several times as biopsy is a sampling.

In brief: Inflammation

Many reasons besides cancer can raise the psa.
Inflammation, infection, prostate stones, stimulation with rectal message or sex could elevate the psa to some degree, but not extremely high levels. Depending on your age and level of elevation one needs to make sure infection has been iliminated and if psa persists or keeps rising rebiopsy is needed several times as biopsy is a sampling.
Dr. Bahman Daneshfar
Dr. Bahman Daneshfar
Thank
2 doctors agree

In brief: High psa

The # matters. Psa can be elevated from inflammation in prostate.
Advil (ibuprofen) reduces inflammation.

In brief: High psa

The # matters. Psa can be elevated from inflammation in prostate.
Advil (ibuprofen) reduces inflammation.
Dr. Richard Sarle
Dr. Richard Sarle
Thank
Dr. James Lin
Urology

In brief: May be...

PSA may rise from infection / inflammation of prostate tissue, and ibuprofen may ease the prostate tissue inflammation if any.
How to interpret its clinical significance has been confusing & conflicting. To clear such information quagmire, go to peruse the articles in http://www.formefirst.com/FreeInfoProstate.html.

In brief: May be...

PSA may rise from infection / inflammation of prostate tissue, and ibuprofen may ease the prostate tissue inflammation if any.
How to interpret its clinical significance has been confusing & conflicting. To clear such information quagmire, go to peruse the articles in http://www.formefirst.com/FreeInfoProstate.html.
Dr. James Lin
Dr. James Lin
Thank
Get help from a real doctor now
Dr. Adam Smith
Board Certified, Internal Medicine
13 years in practice
383K people helped
Continue
108,000 doctors available
Read more answers from doctors