6 doctors weighed in:
What are the benefits of tysabri (natalizumab) v. Other MS drugs?
6 doctors weighed in

Dr. Peter Corrado
Family Medicine
3 doctors agree
In brief: Hard to answer
Tysabri (natalizumab) is a potentially effective treatment for MS but your question would be difficult to answer. Tysabri (natalizumab) is approved for the treatment of aggresive or refractory MS where other equally effective medications have not worked.
This is because of a possibly fatal side effect called pml which may cause more damage than the disease. Use requires an experienced doctor and close monitoring.

In brief: Hard to answer
Tysabri (natalizumab) is a potentially effective treatment for MS but your question would be difficult to answer. Tysabri (natalizumab) is approved for the treatment of aggresive or refractory MS where other equally effective medications have not worked.
This is because of a possibly fatal side effect called pml which may cause more damage than the disease. Use requires an experienced doctor and close monitoring.
Dr. Peter Corrado
Dr. Peter Corrado
Thank
1 comment
Dr. Gael Yonnet
Dr. Corrado is absolutely correct. Tysabri is the most efficacious MS therapy, but it does carry the risk of PML in 1/1000 treated patients and is therefore reserved as a secondary agent when other therapies have failed to afford benefit.
Dr. Andrew Dutka
Neurology
1 doctor agrees
In brief: Monthly injection
Tysabri (natalizumab) is dosed once a month, has fewer side effects day to day, but a big risk of a potentially fatal brain infection with jc virus.
Many patients have been exposed to jc virus. Testing for the virus exposure is available, and if negative the risk of tysabri (natalizumab) is much lower.

In brief: Monthly injection
Tysabri (natalizumab) is dosed once a month, has fewer side effects day to day, but a big risk of a potentially fatal brain infection with jc virus.
Many patients have been exposed to jc virus. Testing for the virus exposure is available, and if negative the risk of tysabri (natalizumab) is much lower.
Dr. Andrew Dutka
Dr. Andrew Dutka
Thank
In brief: Efficacy
Tysabri (natalizumab) is most potent, followed by Gilenya, Tecfidera, Copaxone 40 TIW, Rebif, Aubagio, with equal value of Betaseron, Extavia, Copaxone 20 QD, and last on list is Avonex, least potent.

In brief: Efficacy
Tysabri (natalizumab) is most potent, followed by Gilenya, Tecfidera, Copaxone 40 TIW, Rebif, Aubagio, with equal value of Betaseron, Extavia, Copaxone 20 QD, and last on list is Avonex, least potent.
Dr. Bennett Machanic
Dr. Bennett Machanic
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