5 doctors weighed in:

Which meds help the most with severe depression symptoms?

5 doctors weighed in
Dr. Steven Reidbord
Psychiatry
2 doctors agree

In brief: Most are equal

Doctors choose antidepressants based on side-effect profiles, not superior effectiveness.
Despite minor evidence that older tricyclics may be slightly more effective than more common ssris, it's best to consider antidepressants all equally effective. But for any one patient, one med can work much better than another. Thus, treatment must be tailored to the individual; adding therapy helps too.

In brief: Most are equal

Doctors choose antidepressants based on side-effect profiles, not superior effectiveness.
Despite minor evidence that older tricyclics may be slightly more effective than more common ssris, it's best to consider antidepressants all equally effective. But for any one patient, one med can work much better than another. Thus, treatment must be tailored to the individual; adding therapy helps too.
Dr. Steven Reidbord
Dr. Steven Reidbord
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Tejas Ozarkar
General Practice
2 doctors agree

In brief: Visit a doctor

There are many options when choosing antidepressants (ssris, snris, tricyclics), they vary in their effectiveness, side effects and cost.
However, the most important thing to do is to visit your psychiatrist. They will be able to evaluate if you even need meds or whether there are any other psychiatric issues to address. Make to sure to ask them about side effects of any meds they rx for you.

In brief: Visit a doctor

There are many options when choosing antidepressants (ssris, snris, tricyclics), they vary in their effectiveness, side effects and cost.
However, the most important thing to do is to visit your psychiatrist. They will be able to evaluate if you even need meds or whether there are any other psychiatric issues to address. Make to sure to ask them about side effects of any meds they rx for you.
Tejas Ozarkar
Tejas Ozarkar
Answer assisted by Tejas Ozarkar, Medical Student
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1 comment
Dr. Neil Liebowitz
Most important to note is that severe depression is treatable and don't loose hope if the first few medications don't help. There is no one best medication. It's the process of finding the right one for you. I wrote Psychiatry in Techno Colors to give my clinical pearls on treatment of depression and anxiety. available on amazon.com
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