Does smoking or chewing tobacco cause gene mutations? Which mutations are most common?

Yes. It is thought that there are two mutations necessary to develop squamous cell head and neck cancer, one of which is p53. I'm not certain about gene mutations in other tobacco related cancers or diseases.

Related Questions

Does smoking cause the gums to recede or is it chewing tobacco? I was gueing that chewing cause the gums to deteriorate but some say its smoking. Can I have some opinions?

Tobacco, . Tobacco, in any form, is harmful to your oral and general health. Not only is tobacco one of the major risk factors in the development and progression of gum disease by recession and bone loss and hence tooth loss, it is also associated with oral cancer. Consider quitting stat! Read more...
I . I can assure you that both smoking and chewing are extremely dangerous habits that affect the tissues in the mouth. Chewing has a direct effect on the soft tissues that it comes in contact with and has a link to oral cancer, but both habits cause serious changes in the health of the gums. Seek help to quit either. Read more...
There . There is a direct link with gum disease and nicotine use whether one smokes or chews the tobacco. However, chewing tobacco also adds an extra mechanical way that could adversely affect the gum by causing recession. This is usually more evident where you keep the tobacco in your mouth. I suggest having a dentist or periodontist screen you for oral cancer and gum disease and get some assistance from a professional to quit. Read more...
Both . Both smoking and chewing tobacco can contribute to periodontal disease. This has been firmly established in the periodontal literature. I have seen many patients with periodontal disease on long island which has been caused, or at least greatly accelerated by smoking or snuff use. Here is a short video on the progression of periodontal disease long island . Good luck. Dr. David scharf. Read more...

Can HPV itself cause cancer in penis and oropharynx or do the other risk factors need to be met. Like collection of smegma, smoking chewing tobacco etc?

Synergy. Having more than one risk factor usually raises cancer risk a lot more than just adding up the odds. For penis cancer, HPV plus lack of circumcision is the usual combination of risk factors. For oropharyngeal, the risk is more additive, according to this: http://www.ncbi.nlm.nih.gov/pubmed/27197530. Read more...