5 doctors weighed in:
What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow
5 doctors weighed in

Dr. Quang Nguyen
Internal Medicine - Endocrinology
4 doctors agree
In brief: Discuss
For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy.
Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option.

In brief: Discuss
For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy.
Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option.
Dr. Quang Nguyen
Dr. Quang Nguyen
Thank
Dr. Susan Wingo
Internal Medicine - Endocrinology
1 doctor agrees
In brief: Review with doctor
Follicles are hollow balls with cells on the outside and a protein-containing liquid called colloid on the inside.
Microfollicles are small balls made up almost entirely of cells with very little colloid in the center. Macrofollicles are large balls with much more colloid in the centers. Normal thyroid tissue is mostly macrofollicles, but may include some microfollicles as well.

In brief: Review with doctor
Follicles are hollow balls with cells on the outside and a protein-containing liquid called colloid on the inside.
Microfollicles are small balls made up almost entirely of cells with very little colloid in the center. Macrofollicles are large balls with much more colloid in the centers. Normal thyroid tissue is mostly macrofollicles, but may include some microfollicles as well.
Dr. Susan Wingo
Dr. Susan Wingo
Thank
2 comments
Dr. Susan Wingo
The relative mix is important. More microfollicles would suggest possible tumor (benign adenoma, or possibly cancer)
Dr. Susan Wingo
Hürthle Cells and histiocytes are commonly seen in thyroid FNAs, and by themselves, don't mean much.
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