5 doctors weighed in:
Pca 2001, rrp 2002: psa 2-12, then 500 2010. Orchiectomy dec 2010 then hyperthermia. Psa down to 84 then 6.Now jump up to 120. What do I do now?
5 doctors weighed in

Dr. Steven Ginsberg
Internal Medicine - Hematology & Oncology
4 doctors agree
In brief: Therapy choices
If your testosterone level hasn't been checked, it should be.
If it is not very low, a trial of a gonadotropin releasing hormone agonist (several available) should be the next step. If the testosterone level is low, an antiandrogen (several available) should be tried. Other alternatives include ketoconazole (low or high dose), des, chemotherapy, sipuleucel-t (provenge), clinical trials.

In brief: Therapy choices
If your testosterone level hasn't been checked, it should be.
If it is not very low, a trial of a gonadotropin releasing hormone agonist (several available) should be the next step. If the testosterone level is low, an antiandrogen (several available) should be tried. Other alternatives include ketoconazole (low or high dose), des, chemotherapy, sipuleucel-t (provenge), clinical trials.
Dr. Steven Ginsberg
Dr. Steven Ginsberg
Thank
1 comment
Dr. Steven Ginsberg
If your testosterone is not very low after an orchiectomy, an agonist might be of benefit. However, it is unlikely that you have a high testosterone level. It should be checked.
Dr. Ritesh Rathore
Internal Medicine - Hematology & Oncology
In brief: Re- evaluation
You need a complete re-evaluation with exam, ct abdomen/pelvis and bone scan.
Depending on your overall health the options typically include a trial of oral meds such as ketoconazole, zytiga (abiraterone acetate) followed by more complicated treatments such as Provenge (immunotherapy) and finally chemotherapy. You can also discuss clinical trials with your doctor.

In brief: Re- evaluation
You need a complete re-evaluation with exam, ct abdomen/pelvis and bone scan.
Depending on your overall health the options typically include a trial of oral meds such as ketoconazole, zytiga (abiraterone acetate) followed by more complicated treatments such as Provenge (immunotherapy) and finally chemotherapy. You can also discuss clinical trials with your doctor.
Dr. Ritesh Rathore
Dr. Ritesh Rathore
Thank
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