13 doctors weighed in:

I want to switch back to Lexapro (escitalopram) from zoloft. Is that ok?

13 doctors weighed in
Dr. Steven Reidbord
Psychiatry
6 doctors agree

In brief: Generally yes

Obviously you should talk to your prescribing doc, don't switch behind their back.
They need to know what you're taking, & may have other options to suggest. But yes, it's usually safe & easy to switch between Lexapro (escitalopram) & zoloft. Note that the dosages (mg) are different. Also, zoloft is available as generic while Lexapro (escitalopram) isn't, so Lexapro (escitalopram) costs more & insurance may not cover it.

In brief: Generally yes

Obviously you should talk to your prescribing doc, don't switch behind their back.
They need to know what you're taking, & may have other options to suggest. But yes, it's usually safe & easy to switch between Lexapro (escitalopram) & zoloft. Note that the dosages (mg) are different. Also, zoloft is available as generic while Lexapro (escitalopram) isn't, so Lexapro (escitalopram) costs more & insurance may not cover it.
Dr. Steven Reidbord
Dr. Steven Reidbord
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Dr. Kevin Nasky
Psychiatry
3 doctors agree

In brief: Yes.

As you probably know, both Lexapro (escitalopram) and zoloft are selective serotonin reuptake inhibitors, so switching is not difficult as you're switching within a class.
Secondly, you have already demonstrated that you've both tolerated and responded to zoloft, which should make both you and your doc comfortable. This may require a cross-taper, but your doc will have to decide.

In brief: Yes.

As you probably know, both Lexapro (escitalopram) and zoloft are selective serotonin reuptake inhibitors, so switching is not difficult as you're switching within a class.
Secondly, you have already demonstrated that you've both tolerated and responded to zoloft, which should make both you and your doc comfortable. This may require a cross-taper, but your doc will have to decide.
Dr. Kevin Nasky
Dr. Kevin Nasky
Thank
Dr. Rajal Patel
Family Medicine
3 doctors agree

In brief: Yes

You may be able to switch back to zoloft without any problems.
However, each medication works differently in each individual, so even though Lexapro (escitalopram) and zoloft are in the same class of medications you may have more side effects or a better response with one versus the other.

In brief: Yes

You may be able to switch back to zoloft without any problems.
However, each medication works differently in each individual, so even though Lexapro (escitalopram) and zoloft are in the same class of medications you may have more side effects or a better response with one versus the other.
Dr. Rajal Patel
Dr. Rajal Patel
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Dr. Vadim Baram
Psychiatry
2 doctors agree

In brief: Yes

There is no risk.
Zoloft (sertraline) is also great antidepressant.

In brief: Yes

There is no risk.
Zoloft (sertraline) is also great antidepressant.
Dr. Vadim Baram
Dr. Vadim Baram
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Dr. Paul Schwartz
Psychiatry
2 doctors agree

In brief: Generally no problem

It generally is not a problem switching from Lexapro (escitalopram) to zoloft, since they are in the same class of antidepressant medications.
However, there are a number of considerations (e.g. What dosage of Lexapro (escitalopram) are you on; what dosage of zoloft are you hoping to achieve; how fast can the switch be made) that should be discussed with your doctor before making the switch.

In brief: Generally no problem

It generally is not a problem switching from Lexapro (escitalopram) to zoloft, since they are in the same class of antidepressant medications.
However, there are a number of considerations (e.g. What dosage of Lexapro (escitalopram) are you on; what dosage of zoloft are you hoping to achieve; how fast can the switch be made) that should be discussed with your doctor before making the switch.
Dr. Paul Schwartz
Dr. Paul Schwartz
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Dr. Douglas Bey
Psychiatry
2 doctors agree

In brief: No problem

They are both ssris--your doc should make the final decision.

In brief: No problem

They are both ssris--your doc should make the final decision.
Dr. Douglas Bey
Dr. Douglas Bey
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Dr. Gregory Hines
Family Medicine
2 doctors agree

In brief: They are similar

Both are ssri type antidepressants, and can be substituted for each other. However, Lexapro (escitalopram) is a second generation antidepressant, and is often more effective than your zoloft.

In brief: They are similar

Both are ssri type antidepressants, and can be substituted for each other. However, Lexapro (escitalopram) is a second generation antidepressant, and is often more effective than your zoloft.
Dr. Gregory Hines
Dr. Gregory Hines
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