6 doctors weighed in:
Besides genetics, what determines the chance of a solid thyroid nodule being cancerous? I have a solid nodule that has grown fast and normal TSH level
6 doctors weighed in

Dr. Lori Wagner
Internal Medicine
3 doctors agree
In brief: Cancer risk
Risk of cancer is higher in patients < 20 and > 70, and in males.
Concern for cancer higher if fixed (non-mobile), fast growing, lymph nodes in the neck, firm/hard, history of neck radiation, problems swallowing/talking/breathing. A TSH that is normal is actually more concerning as well. Typically if > 1cm and normal tsh, biopsy is performed. Especially if any other risk factors present.

In brief: Cancer risk
Risk of cancer is higher in patients < 20 and > 70, and in males.
Concern for cancer higher if fixed (non-mobile), fast growing, lymph nodes in the neck, firm/hard, history of neck radiation, problems swallowing/talking/breathing. A TSH that is normal is actually more concerning as well. Typically if > 1cm and normal tsh, biopsy is performed. Especially if any other risk factors present.
Dr. Lori Wagner
Dr. Lori Wagner
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Dr. Quang Nguyen
Internal Medicine - Endocrinology
1 doctor agrees
In brief: Risk
Agree with dr. Wagner's answer. Thyroid nodules are common, however, personal history of excess radiation to the neck or family history of thyroid cancer are two strong risk factors.
Depending on the original size, rapidly growing solid nodule need to be evaluated with a biopsy. Tsh can be normal in thyroid cancer. When in doubt, biopsy it.

In brief: Risk
Agree with dr. Wagner's answer. Thyroid nodules are common, however, personal history of excess radiation to the neck or family history of thyroid cancer are two strong risk factors.
Depending on the original size, rapidly growing solid nodule need to be evaluated with a biopsy. Tsh can be normal in thyroid cancer. When in doubt, biopsy it.
Dr. Quang Nguyen
Dr. Quang Nguyen
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Dr. Hung Khong
Internal Medicine - Oncology
In brief: Fast growing nodule
Most people with thyroid nodules have normal tsh.
Less than 1% of nodules cause hyperthyroidism or thyrotoxicosis. Five percent (5%) of all palpable thyroid nodules are cancerous. Therefore, a fast growing solid nodule with a normal TSH should be biopsied to rule out malignancy. Risks : male, extreme age (<20 or >65), fast growing nodule, symptoms, history of radiation to head/neck, family history.

In brief: Fast growing nodule
Most people with thyroid nodules have normal tsh.
Less than 1% of nodules cause hyperthyroidism or thyrotoxicosis. Five percent (5%) of all palpable thyroid nodules are cancerous. Therefore, a fast growing solid nodule with a normal TSH should be biopsied to rule out malignancy. Risks : male, extreme age (<20 or >65), fast growing nodule, symptoms, history of radiation to head/neck, family history.
Dr. Hung Khong
Dr. Hung Khong
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