11 doctors weighed in:
Under what conditions would you prescribe an maoi for depression?
11 doctors weighed in

Dr. Mark Reynolds
Psychiatry
5 doctors agree
In brief: MAOIs
In most cases maois are used when other antidepressants are ineffective.
They are likely under utilized due to concerns over drug drug interactions and dietary restrictions leading most younger psychiatrists to lack expertise. One maoi, Emsam is available in a patch, which avoids oral absorption and can be a nice alternative for those that have undergone some forms of gastric bypass surgery.

In brief: MAOIs
In most cases maois are used when other antidepressants are ineffective.
They are likely under utilized due to concerns over drug drug interactions and dietary restrictions leading most younger psychiatrists to lack expertise. One maoi, Emsam is available in a patch, which avoids oral absorption and can be a nice alternative for those that have undergone some forms of gastric bypass surgery.
Dr. Mark Reynolds
Dr. Mark Reynolds
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Dr. David Hunter
Psychiatry
4 doctors agree
In brief: Later choice
Monoamine oxidase inhibitors are no longer the first choice of antidepressant, in part because of dietary restrictions and other side effects.
Most psychiatrists would not prescribe one unless the patient had been treated successfully with one in the past or if the patient had failed one or more of the first choice medications available.

In brief: Later choice
Monoamine oxidase inhibitors are no longer the first choice of antidepressant, in part because of dietary restrictions and other side effects.
Most psychiatrists would not prescribe one unless the patient had been treated successfully with one in the past or if the patient had failed one or more of the first choice medications available.
Dr. David Hunter
Dr. David Hunter
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Dr. Arman Danielyan
Pediatrics - Psychiatry
In brief: MAOIs
Maois are typically used for treatment resistant depression, when other treatment modalities fail.
They are also used for treatment of so called "atypical" depression which is characterised by increased sleep and appetite.

In brief: MAOIs
Maois are typically used for treatment resistant depression, when other treatment modalities fail.
They are also used for treatment of so called "atypical" depression which is characterised by increased sleep and appetite.
Dr. Arman Danielyan
Dr. Arman Danielyan
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Dr. James Fox
Psychiatry
In brief: Failed treatment
There is no precise answer but in general, people have not had success with several adequate trials of anti-depressants.
They can be more complicated to start since you should be off an ssri, snri or tca for at least 2 weeks prior to starting it (5 weeks for prozac) and there are diet restrictions for oral maois. There is a selegiline patch (emsam) without those diet restrictions.

In brief: Failed treatment
There is no precise answer but in general, people have not had success with several adequate trials of anti-depressants.
They can be more complicated to start since you should be off an ssri, snri or tca for at least 2 weeks prior to starting it (5 weeks for prozac) and there are diet restrictions for oral maois. There is a selegiline patch (emsam) without those diet restrictions.
Dr. James Fox
Dr. James Fox
Thank
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