I'm currently takung aciphex (rabeprazole) for acid reflux. I was also treated for an STD and was given azithromycin. Will the aciphex (rabeprazole) interfere with the zithromax?

No interaction . There's no interaction as far as I am aware and believe they should be safe to take together.
Probably Not. According to the Aciphex website, in clinical trials using combination therapy with rabeprazole plus Amoxicillin and Clarithromycin (which is similar to azithromycin), no adverse reactions unique to this drug combination were observed.