Is combination of tramadol hydrochloride nd acetaminophen an effective nd safe medicine as pain killer in parkinson for an aged female for long term?

Should be. Tramadol and tylenol (acetaminophen) in prescribed and recommended doses for the elderly should be safe to take and effective.
NO. Severe pain to need tramadol is a little unusual in parkinson's disease. Long term pain medications are not a good idea as they cause resistance to meds as well as causing addiction. Pain pills are for acute treatment in most cases do see a neurologist to find out the source of the problem, there are other ways of treating pain than giving analgesics.