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Is it real that januvia (sitagliptin) 100mg made pancreas cells produce more insulin ( made beta cells more active )?

1 doctor weighed in
Dr. David Sneid
Internal Medicine - Endocrinology

In brief: Incretin

Januvia (sitagliptin) is an incretin which inhibits the breakdown of an enzyme called dpp-4.
Dpp-4 breaks down glp-1. Glp-1 stimulates Insulin and inhibits glucagon (which raises glucose). Inhibition of glp-1 breakdown means it can stimulate more Insulin and inhibit more glucagon.

In brief: Incretin

Januvia (sitagliptin) is an incretin which inhibits the breakdown of an enzyme called dpp-4.
Dpp-4 breaks down glp-1. Glp-1 stimulates Insulin and inhibits glucagon (which raises glucose). Inhibition of glp-1 breakdown means it can stimulate more Insulin and inhibit more glucagon.
Dr. David Sneid
Dr. David Sneid
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