Effect vary c all.. Corticosteroids are naturally secreted by the adrenal glands sitting atop the kidneys. Medically, pills, inhalers, topicals are used. Rx asthma, autoimmune diseases (body makes antibodies against its own cells), severe arthritis, rashes. Many side effects from all, taking or stopping. Lowest dose possible (delivery thru skin, nose, lungs) is best to avoid mood swings, etc. Must be rx by doctor.