NEED ANSWER Have an elder aunt 75 diag. Klebsiella bact. Uti, since bowels have changed, bowel meds not very helpful. Macrobid not working (2 rounds of treatment. Behavior/personality changes what else can I do or what else can be wrong?

Many possibilities. From a bowel condition causing constipation, benign or malignant to a metabolic disorder, such as hypothyroidism, including poorly defined neurological disorders from the dementia spectrum, anything is possible. She needs a good workup with her doc that should expand past the UTI that is not likely to be causing the problems, but rather the late effect of them.