Is it OK to take Venlafaxine 150mg and also take Propranolol 100mg?

Interactions. Both medications affect epinephrine and propanolol can cause tiredness which can be confused with depression. Your pharmacist has more information about the taking of these 2 medications together. My sense is that venlaxifine would override any mood effects caused by propranolol. Patients with migraine have taken the 2 medications without problems. In addition your psychiatrist may have experience.