2 doctors weighed in:

Periods regular. started phentermine June 2017, regular cycles, no drastic weightloss nor drastic changes in diet. Last cycle was 3 days, typically 5-7 . now no cycle for 44 days. breasts tender, moody, nausea. Spouse had vasectomy. Pregnancy?

2 doctors weighed in
Dr. Timothy Brown
Obstetrics & Gynecology
1 doctor agrees

In brief: Pregnancy unlikely

But you still need to rule out pregnancy first.
There are many home pregnancy tests that work well and should be positive by now on the off chance that you are pregnant. Although you have had no "drastic" weight loss it still could be enough to affect your cycles. Also women in their 40's naturally become less regular even though full menopause may be many years away.

In brief: Pregnancy unlikely

But you still need to rule out pregnancy first.
There are many home pregnancy tests that work well and should be positive by now on the off chance that you are pregnant. Although you have had no "drastic" weight loss it still could be enough to affect your cycles. Also women in their 40's naturally become less regular even though full menopause may be many years away.
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