Is the tech available to modify or select for certain alleles to prevent an autosomal recessive disease in offspring? Alpha 1 antitrypsin def. I'm MS husband MZ. We're considering having a child and would like to avoid the 25% chance of the child SZ

Probably not. Research is ongoing but far from available to the public. You might consult with a fertility clinic. You could create some embryos selectively implant only those with an acceptable gene profile. This is both controversial & would be expensive with no guarantee of a successful pregnancy. But the tech is available.