2 doctors weighed in:

Does the woman’s body prevents sperm containing de novo single gene mutation, from fertilizing the egg and develop into a child with disorders?

2 doctors weighed in
1 doctor agrees

In brief: No.

A single mutation CAN enter your baby's genome.
And always DOES! In fact, the average person has several hundred DNA flaws, many of which could lead to diseases. http://www.medicaldaily.com/nobodys-perfect-we-all-carry-400-disease-causing-dna-mutations-243809 . Bottom line - DON'T WORRY. If a serious illness runs in the father's (your?) family, consider a genetic counselor.

In brief: No.

A single mutation CAN enter your baby's genome.
And always DOES! In fact, the average person has several hundred DNA flaws, many of which could lead to diseases. http://www.medicaldaily.com/nobodys-perfect-we-all-carry-400-disease-causing-dna-mutations-243809 . Bottom line - DON'T WORRY. If a serious illness runs in the father's (your?) family, consider a genetic counselor.
Dr. Scott Welker
Dr. Scott Welker
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