The skin on the center of my chest has been itching and slightly burning on and off for the past two days. Could this be a symptom of heart disease or other problem?

Likely a skin issue . If it is your skin that is itchy and burning it is likely a skin issue. Is there discoloration? Have you put something on the area that may have caused a reaction? Best to see a doctor if it is persistent to evaluate etiology and treatment plan. .