I am being prescribed Lexapro, wellbutrin and elavil for depression and anxiety. Is this combo safe?

Drug Interactions. Elavil (amitriptyline) + Wellbutrin (bupropion) ^ es seizure risk. Escitalopram +amitriptyline ^'es risk of serotonin syndrome. Wellbutrin + Lexapro ^es seizure risk. I am assuming that the Elavil is added in for insomnia or pain control and not for depression/ anxiety. This does not mean that these drugs can't be used together but there are possible drug interactions. D/W your physician.