Clindesse and alcohol? How long after the one dose should I wait

Clindamycin. It is better not to drink alcohol on the days you are on antibiotics as alcohol can affect clindamycin's pharmacology as well as add to side effects of clindamycin . If abstinence not practical then only light drinking after 4 hours or more can be ok. Medicine is eliminated by gall bladder and kidneys and chronic alcohol use can decrease function of these as well. .
No major problem, if. NO major problem if you're talking about a small amount of alcohol, a glass of wine or a beer.; Clindesse is a topical anti-bacterial for vaginitis, and is not heavily absorbed systemically. Thus drinking in moderation should not have any significant effect on the treatment and should not induce problematic side effects.