2 doctors weighed in:

Can i take 500mg methocarbamol with my usual 20mg nortriptyline for an unusually bad attack of trigeminal neuralgia? I have a dr appmt in 6 days

2 doctors weighed in
Dr. Bert Liang
Neurology
1 doctor agrees

In brief: Not advised

Because both drugs are nervous system depressants, there is a potential for at least an additive effect.
Spacing out the medications and avoiding activities like driving or operating machinery would be a start.

In brief: Not advised

Because both drugs are nervous system depressants, there is a potential for at least an additive effect.
Spacing out the medications and avoiding activities like driving or operating machinery would be a start.
Dr. Bert Liang
Dr. Bert Liang
Thank
Dr. Heidi Fowler
Psychiatry

In brief: Drug interactions.

Per Drugs.Com drug interaction checker there is possibility of moderate interaction.
"Using nortriptyline together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination." See:

In brief: Drug interactions.

Per Drugs.Com drug interaction checker there is possibility of moderate interaction.
"Using nortriptyline together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination." See:
Dr. Heidi Fowler
Dr. Heidi Fowler
Thank
1 comment
Dr. Heidi Fowler
https://www.drugs.com/interactions-check.php?drug_list=1588-0,1734-0. This does not mean you can't take them together - but I always recommend you discuss it with your physician first.
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