What are the common causes of relative lymphopenia, and low absolute monocytes? Low B12, low D25. CBC diff. I have lost a huge amount of weight also.

It could be serious. Unintended weight loss is always a matter of serious concern about your health. You should go see a doctor for a physical exam and have a medical check up to find the cause of your weight loss and check your blood and do other appropriate tests to get you well. Lymphopenia can be a sign of immune deficiency. So a repeat check of CBC and differential blood counts are important to do.

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What are the common causes of relative lymphopenia, and low absolute monocytes? Low B12, low D25. CBC/ diff. I have lost a huge amount of weight also.

Weight loss. Your "huge" weight loss, if unintentional due to poor appetite, is a potentially serious symptom, probably a lot more important than having low lymphocyte or monocyte counts. See a doctor soon; or if already in care, discuss your ongoing symptoms and other concerns with your doctor. Read more...