2 doctors weighed in:

How long should I wait to take Pepto Bismol after taking seizure meds (Depakote, Aptiom, Topirimate)?

2 doctors weighed in
Dr. Charles Cattano
Internal Medicine - Gastroenterology
1 doctor agrees

In brief: Depakote problematic

Drugs.com identifies no interactions of PeptoBismol with Aptiom or topiramate.
Also, small single doses of salicylates are unlikely to cause significant effects with Depakote. However, patients who take large doses of salicylates or over a prolonged period of time should be closely monitored for clinical & laboratory evidence of valproate toxicity and hepatotoxicity. Ref: drugs.com

In brief: Depakote problematic

Drugs.com identifies no interactions of PeptoBismol with Aptiom or topiramate.
Also, small single doses of salicylates are unlikely to cause significant effects with Depakote. However, patients who take large doses of salicylates or over a prolonged period of time should be closely monitored for clinical & laboratory evidence of valproate toxicity and hepatotoxicity. Ref: drugs.com
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