To control CHF is it normal to prescribe hydralazine alone or with isosorbide dinitrate? She has no hypertension, but AF. Headache+AF worsens wt these

Yes. The combination of hydralazine and isosorbide reduce filling pressures in the heart, reduce the amt of work the heart must do, & reduce the changes in structure to the heart that heart failure brings. This is for heart failure where the ejection fraction is less than 40%. .

Related Questions

How does isosorbide dinitrate and hydralazine work in treating congestive heart failure?

A-HEFT Trial. A large trial looked at the combination of hydralazien and Isordil (isosorbide dinitrate) with african american patients and showed a benefit of improving heart failure status, on top of standard medical therapy. It is thought to be believed due to lack of Nitric Oxide delivery to endothelium in african americans, that is improved by this therapy. Blood pressure tends to be higher in the first place, which improves. Read more...