1 doctor weighed in:

Can CH50 & C1 Esterase Inhibitor be WNL with decreased C3/C4 levels? I've been diagnosed with Anemia, Gatroparesis, SLE & MCTD to date

1 doctor weighed in
Dr. Al Hegab
Internal Medicine - Allergy & Immunology

In brief: Yes, 2 different

conditions, and low C3/C4 is due to complement consumption in autoimmune diseases as SLE or MCTD.
CH50 is the mean of hemolytic complement, and is low in complement defiency, rare, while C1 Esterase is deficient manly in Hereditary Angioedema, all not related to SLE / MCTD, wish you all the best

In brief: Yes, 2 different

conditions, and low C3/C4 is due to complement consumption in autoimmune diseases as SLE or MCTD.
CH50 is the mean of hemolytic complement, and is low in complement defiency, rare, while C1 Esterase is deficient manly in Hereditary Angioedema, all not related to SLE / MCTD, wish you all the best
Dr. Al Hegab
Dr. Al Hegab
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