Would large ovarian cyst cause periods 2 weeks apart and now 19 days late on following cycle. Neg pregnant test at 8 days late. My dr shrugged when asked?

Yes it can. Not sure how big is big to you, but if this is a follicular cyst (egg cyst) and is persistent because you didn't ovulate, it can cause delayed menses or irregular breakthrough bleeding. Normal mature follicles are usually around 2-2.5cm.