Given a positive RNP antibody test, what are the clinical diagnostic criteria for MCTD?

MCTD. Usually considered diagnostic if high RNP titer, and two or more of the following: Raynauds, myositis, synovitis and swollen fingers/hands.

Related Questions

I was just diagnosd with mctd...No symptoms just rnp antibody of 1.9 and anachoice screen-positive...What lies ahead for me?

Diagnosis? Connective tissue diseases can only be diagnosed if a person has symptoms and physical signs of a disease. Mctd cannot be diagnosed by blood test alone as a percent of the normal population has a positive rnp without any disease. It is not like checking your blood type (a positive, o negative, etc.). Ask your doctor how the diagnosis of mctd was made. Read more...
Lab not impressive. The lab results you describe are unimpressive and not suggestive of a mctd, especially in an individual with not symptoms. Why were the tests done in the first place if you have no symptoms? It makes no sense to me but i doubt the diagnosis. See a rheumatologist. Read more...

Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

Heads up. One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. Read more...

I was just diagnosd with mctd rnp antibody of 1.9 and anachoice screen-positive the only symptom is joint pain in my hand/wrist (i do have carpal tnl?

Positive Labs. Positive labs are meaningless unless you have symptoms. At this point, your doctor is aware of the positive results and will likely follow your symptoms. The positive simply means you are at a greater chance of developing symptoms though not everybody does. Read more...
Not sure. It is difficult to truly assess whether you have mctd or not. The presence of the rnp antibody in your blood does not mean anything by itself; you must have symptoms that can be attributed to this. Not having mctd does not rule out other autoimmune disease. Technically, when I am confident of a mctd diagnosis, i see some muscle weakness, mild raynaud's/sclerodactyly, and joint stiffness/swelling. Read more...