18 doctors weighed in:

Is Zoloft (sertraline) bad for my liver?

18 doctors weighed in
Dr. Horacio Capote
Psychiatry
14 doctors agree

In brief: Probably Not

Although metabolized by the liver, zoloft (sertraline) is one of the milder antidepressants on the liver. If you are very concerned you can ask your doc to check your liver enzymes.

In brief: Probably Not

Although metabolized by the liver, zoloft (sertraline) is one of the milder antidepressants on the liver. If you are very concerned you can ask your doc to check your liver enzymes.
Dr. Horacio Capote
Dr. Horacio Capote
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Dr. Alan Ali
Psychiatry
1 doctor agrees

In brief: Zoloft (sertraline)

As long as your liver profile testing is normal, no worries.

In brief: Zoloft (sertraline)

As long as your liver profile testing is normal, no worries.
Dr. Alan Ali
Dr. Alan Ali
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Dr. Leonard Lado
Psychiatry
1 doctor agrees

In brief: Zoloft (sertraline) and liver

Zoloft (sertraline) is metabolized after going thru stomach anf liver by an enzyme cpy2b6.
If this enzymes has an abnormal rate of metabolism which can be measure with a simple genetic test called assurerx it then gets excreted in the kidney half its amount in 26 hours. So the drug like any other does not necessarily cause liver disease but liver disease can affect how a drug is processed leading poor results.

In brief: Zoloft (sertraline) and liver

Zoloft (sertraline) is metabolized after going thru stomach anf liver by an enzyme cpy2b6.
If this enzymes has an abnormal rate of metabolism which can be measure with a simple genetic test called assurerx it then gets excreted in the kidney half its amount in 26 hours. So the drug like any other does not necessarily cause liver disease but liver disease can affect how a drug is processed leading poor results.
Dr. Leonard Lado
Dr. Leonard Lado
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