Can you be allergic to sperm?

Sperm allergy. Absolutely. Allergic reactions during intercourse are well described whether from sperm, spermicide or latex condoms. While vaginal and perivaginal itching is a frequent complaint, there have been reports of anaphylaxis. Successful treatment can consist of use of various barrier devices like condoms, pretreatment with various topical meds and/or immunotherapy with the allergenic sperm protein.