1 doctor weighed in:

Does spironolactone actually increase basal levels of estrogen or does it just block androgens, decreasing testosterone?

1 doctor weighed in
Dr. Clarence Grim
Internal Medicine - Endocrinology

In brief: Spironolactone

26F NY asks: Does spironolactone actually increase basal levels of estrogen or does it just block androgens, decreasing testosterone? ANS: complex: decrease T production by testis, increases T conversion to E2 so more estrogen and displaces T from SHBG.
Binds with T receptors thus acting like anti T. I specialize in BP and diet and drug RX. Happy to do 2nd opinion.

In brief: Spironolactone

26F NY asks: Does spironolactone actually increase basal levels of estrogen or does it just block androgens, decreasing testosterone? ANS: complex: decrease T production by testis, increases T conversion to E2 so more estrogen and displaces T from SHBG.
Binds with T receptors thus acting like anti T. I specialize in BP and diet and drug RX. Happy to do 2nd opinion.
Dr. Clarence Grim
Dr. Clarence Grim
Thank
Get help from a real doctor now
Dr. Umesh Patel
Board Certified, Preventive Medicine
40 years in practice
1M people helped
Continue
111,000 doctors available