Sir, my sister got Multiple small peripherally arranged follicles in both ovaries and Stroma is thickened & echogenic. It it a matter of big panic? I

Sonogram report. It is important that radiologic studies be interpreted within the clinical context. The doctor ordering the test will need to help you interpret the sonogram as they know details about her medical history. It sounds like the report describes polycystic ovarian syndrome. If she has irregular periods then this could fit. Confirm with her doctor.
Never panic! But this is likely to be best treated ASAP. She needs to discuss the results w/ her Dr and follow the recommendations as well and soon as possible. Panic will not help. After hearing the plan, she'll know how risky a wait will be. Getting the info is important to do NOW!