What is the definition or description of: Neural tube defect?

Neural tube defect. Neural tube defects are birth defects of the brain, spine, or spinal cord. They happen in the first month of pregnancy, often before a woman even knows that she is pregnant. The most common neural tube defects are spina bifida, anencephaly, and encephalocele.

Related Questions

What is the best neural tube defect test?

NTD. The "best" test is an amniotic fluid AFP concentration. That picks up about 90% of open neural tube defects. However, an ultrasound examination also picks up the majority of open neural tube defects. Read more...

What are the tests for neural tube defect?

Neural tube defects. The primary test is the maternal serum fetal protein. If that is abnormal, an ultrasound examination and perhaps an amniocentesis. Read more...
Ultrasound, MSAFP. Prenatal ultrasound should have >90% sensitivity for open neural tube defect detection around 20 weeks. Earlier (>16 weeks) risk stratification can occur with screening maternal blood for AFP - although that is not diagnostic and has to be followed by ultrasound for confirmation and/or differential diagnosis. Fetal MRI is used as part of evaluation for possible fetal surgery to treat spina bifida. Read more...

I want to know what's the neural tube defect test?

2 tests. To diagnose a neural tube defect the two most useful tests are 1) The mother's blood level of a protein that lines the inner surface of the developing spinal cord in the fetus, called alpha fetoprotein, and 2) a fetal or newborn ultrasound of the spinal canal itself. Other radiologic tests such as X-Ray films, CT scans, and MRI scans help to get a clearer picture of the neural tube defect. Read more...

What is the chance of having another child with a neural tube defect?

8x greater risk. It has been shown that having a child with a neural tube defect increases the chance of having a second child with a similar defect. The recurrence risk in this situation is 8 times greater than the risk if no such history was present. Also if there is any family history of neural tube defects there is an increased risk of an affected pregnancy even if not immediate relative (2cd or 3d degree). Read more...

I have a high positive for increased open neural tube defect, now what?

Additional screening. A positive initial screening test should be followed by a more involved and dependable test looking for this possibility.A diagnostic high resolution ultrasound can be performed that can evaluate baby from top to bottom and see if there is any direct evidence of a problem. Discussion of these findings with a geneticist or perinatologist may then be needed if the problem is not excluded by the test. Read more...

Which is the chance of having more then one child with a neural tube defect?

NT defect. This depends on the cause of the defect, but overall, your risk for a second child with a neural defect increases after you have a child with a defect. Your OB will likely suggest taking a higher dose of folic acid when you are thinking of conceiving. Read more...

What kind of likelihood is there of having more then one child with a neural tube defect?

It varies. If parents have had one child with a neural tube defect their risk of having another child with a defect is about 3 %. If they have had two children with the defect their risk increases to about 7 %. A parent who has a neural tube defect also has about a 3 % risk of having a child with a neural tube defect. All of these risks can be lowered significantly by maternal Folic Acid ingestion. Read more...
NT Recurrence rate. If you have one child with a neural tube defect, chances are higher that a second child will have one are 10-30x's that of the general population, between 1 in 40 and 1 in 100 depending on type of defect. Read more...

Are neural tube defect babies active?

Possibly. It depends on multiple factors. There are different degrees of neural tube defects. Some people can have a mild defect and other may have a severe defect. It also depends on the location of the defect. Your doctor might be able to better answer this question with all of the relevant information. Read more...

Can you tell me how is neural tube defect diagnosed after birth (not prenatally)?

Physical exam. NTD's can form from one end of the nervous system to the other. The most common is spina bifida cystica with a sac of the inferior spinal cord and a skin opening near the lower end of the spine.Hidden defects in the area may be suspected on close exam. NTD at the neck can have a sac of neural tube coverings, Anencephaly, with an open skull is also obvious. Read more...