What is the definition or description of: Fragile X syndrome?

Fragile X. Fragile X syndrome is a genetic disorder. The abnormality is found on mutation of the fragile X mental retardation 1 (FMR1) gene on the X chromosome. The mutation is repetition of FMR1 gene Affected males have intellectual and developmental delays and 33% of affected females have intellectual delays. Affected individuals may have large heads and long faces.

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How common is fragile x syndrome in us?

Depends on your dfn. Significant impairment (iq<70) in FAS is felt to represent 1/3600 of the population, mostly male. A lesser form of involvement with lesser alterations in this gene (add, behavior issues) may affect 1/130-250 female & 1/250-800 males. See: www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc2888470/?Tool=pmcentrez. Read more...