Why are my hands swelling and itching?

Other symptoms? Although itching can be caused allergies, compression neuropathies such as carpal tunnel syndrome should also be considered if you have numbness and/or tingling. The numbness is usually worse at night and in the morning. It can also develop during activities such as brushing your teeth, talking on the phone, and driving a car. See a board certified dermatologist or hand surgeon for a evaluation.
Allergy? Have you taken a new medicine or been exposed to something new? Swelling and itching are often signs of an allergic reaction to something. If you don't think it could be allergic, how long has it been going on? Any change in activity or injury? Any numbness?