3 doctors weighed in:

ALT 61. AST and rest of LFT's normal. Is this concerning? Taking Lipitor, (atorvastatin) possible cause? PCP not concerned. Should he be? Should be?

3 doctors weighed in
Dr. Gurmukh Singh
Pathology
2 doctors agree

In brief: No, see below

Statins increase alanine aminotransferase (ALT) concentrations (one of the enzymes from the liver) in 10% of recipients, and this increase can exceed more than three times the upper limit of normal in 1% of patients.
Despite a lack of evidence that statins cause liver disease, many physicians are reluctant to start statins in patients with an out-of-range ALT value. Most patients with high ALT will have fatty liver or non-alcoholic steatohepatitis (NASH), because 20% or more of patients in developed countries have these conditions (i.e., a fifth of people in developed countries have fatty liver or NASH, and on occasion many, but not all, have abnormal ALTs)

In brief: No, see below

Statins increase alanine aminotransferase (ALT) concentrations (one of the enzymes from the liver) in 10% of recipients, and this increase can exceed more than three times the upper limit of normal in 1% of patients.
Despite a lack of evidence that statins cause liver disease, many physicians are reluctant to start statins in patients with an out-of-range ALT value. Most patients with high ALT will have fatty liver or non-alcoholic steatohepatitis (NASH), because 20% or more of patients in developed countries have these conditions (i.e., a fifth of people in developed countries have fatty liver or NASH, and on occasion many, but not all, have abnormal ALTs)
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