Anti ro ssa was low but present. Anti TG antiTpo antibodies elevated but ana w/ panel was (-) euthyroid. Has s/s responds to plaquenil (hydroxychloroquine) Differential Dx?

Sjögren's syndrome. Anti-ssa antibodies are most commonly associated with Sjögren's syndrome, but it does not confirm a diagnosis. Pts should may have symptoms of dry eyes and dry mouth, which are classic for Sjögren's syndrome. These ab's are also associated with connective tissue diseases such as lupus or SLE. However, a pt must have clinical and lab abnormalities to meet the diagnosis. .