1 doctor weighed in:

Can I safely take cetirizine or any antihistamine AFTER drinking alcohol? For exemple in case of allergic reaction right after/during a party?

1 doctor weighed in
Dr. John Chiu
Internal Medicine - Allergy & Immunology

In brief: Usually

but the older antihistamines (Benadryl (diphenhydramine) (diphenhydramine) etc) tends to cause additive drowsiness effect to alochol.
A rule of thumb is that a Benadryl (diphenhydramine) 25 mg= 1 shot of alcohol in sedation. The newer ones don't have this issue.

In brief: Usually

but the older antihistamines (Benadryl (diphenhydramine) (diphenhydramine) etc) tends to cause additive drowsiness effect to alochol.
A rule of thumb is that a Benadryl (diphenhydramine) 25 mg= 1 shot of alcohol in sedation. The newer ones don't have this issue.
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