2 doctors weighed in:

Is Down Syndrome a sex linked chromosomal disease?

2 doctors weighed in
Dr. James Ferguson
Pediatrics

In brief: No

Down syndrome is an abnormality of chromosome numbers, not a mutation on a sex chromosome.
During conception only one of chromosome of each pair is given by both parents to the fertile egg.If a parent adds their 2 # 21 chm to the other parents # 21, 3 end up in the egg ; the excess 21 causes the all the problems.Rare forms are causes by a extra piece of a 21, but that's another issue.

In brief: No

Down syndrome is an abnormality of chromosome numbers, not a mutation on a sex chromosome.
During conception only one of chromosome of each pair is given by both parents to the fertile egg.If a parent adds their 2 # 21 chm to the other parents # 21, 3 end up in the egg ; the excess 21 causes the all the problems.Rare forms are causes by a extra piece of a 21, but that's another issue.
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Dr. Maya Vazirani
Pediatrics - Neonatology

In brief: No

it involves chromosome 21 an extra copy-trisomy and translocsation of acrocentric chromosomes andvchromosome 21

In brief: No

it involves chromosome 21 an extra copy-trisomy and translocsation of acrocentric chromosomes andvchromosome 21
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