5 doctors weighed in:

Can peptic ulcer disease lead to cancer?

5 doctors weighed in
Dr. Shaban Faruqui
Internal Medicine - Gastroenterology
2 doctors agree

In brief: Hp -Pud-CA in some

H. pylori infection can lead to chronic gastritis, atrophy of mucosa, and fibrosis with intestinal metaplasia, this change increase risk of Cancer, in addition genetic susceptibility contributes.
H.pylori is strongly linked to gastric cancer and is now classified as a group I carcinogen.Of interest H. pylori infection may protect against esophageal adenocarcinoma through reduction in gastric acid

In brief: Hp -Pud-CA in some

H. pylori infection can lead to chronic gastritis, atrophy of mucosa, and fibrosis with intestinal metaplasia, this change increase risk of Cancer, in addition genetic susceptibility contributes.
H.pylori is strongly linked to gastric cancer and is now classified as a group I carcinogen.Of interest H. pylori infection may protect against esophageal adenocarcinoma through reduction in gastric acid
Thank
1 comment
Dr. Shaban Faruqui
Gastric ulcer disease and gastric cancer have etiologic factors in common. A likely cause of both is atrophic gastritis induced by H. pylori. By contrast, there appear to be factors associated with duodenal ulcer disease that protect against gastric cancer.Helicobacter pylori infection is now recognized as an important causative factor in both duodenal ulcers and gastric cancer.
Dr. Gurmukh Singh
Pathology
1 doctor agrees

In brief: Rarely

Peptic ulcers and stomach cancer are both caused, in part, by helicobacter infection.
A stomach cancer may present as an ulcer. A bona fide peptic almost never turns into cancer.

In brief: Rarely

Peptic ulcers and stomach cancer are both caused, in part, by helicobacter infection.
A stomach cancer may present as an ulcer. A bona fide peptic almost never turns into cancer.
Thank
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