I normally take tylenol (acetaminophen) if I have a headache. But is it better to take something like advil or aleve if I had a headache after a night of drinking?

Hanover headache. Tylenol (acetaminophen) for hangover headaches doesn't do much, according to my patients. Aleve liquid caplets seem to help the best. 1-2 tabs can last 12-24 hours. Or you can also try exceedrin migraine, which has some caffeine (small amount), Tylenol (acetaminophen) and aspirin. My patients have also had good results with this.