Can I take Nexium (esomeprazole) and NyQuil?

Which NyQuil? Turns out, there are many versions of NyQuil, each w/different medications/ingredients. So while it's wise to check for interactions, you need to be more specific. Check out http://www.drugs.com/interactions-check.php?drug_list=1015-567,55-17410,54-16419 where I ran 2 common versions against Nexium (esomeprazole) - looks fine. You can always ask local pharmacist or your Family Doc, too. Above assumes no allergie.