Going from 60mg Prozac to 50mg of pristiq (desvenlafaxine). How long before I feel full benefits of pristiq (desvenlafaxine)?

Medications effects. I understand your need for improvement in depression for which you have taken Prozac (fluoxetine). Thank you for information about use of Morphine. Using Prozac (fluoxetine) with Morphine may increase dizziness, some impairment in thinking and judgment. Please do not withdraw from high dose of 60mg/day Prozac (fluoxetine) quickly due to risk of severe side effects. See a Psychiatrist for gradual withdrawal, and then discuss Prisitiq.