1 doctor weighed in:

Benadryl (diphenhydramine) tabs take about 1 hour to start working to treat my allergic reaction (rash) Would Benadryl (diphenhydramine) IM be a faster alternative? Can I obtain an RX?

1 doctor weighed in
Dr. John Chiu
Internal Medicine - Allergy & Immunology

In brief: Depends

Benadryl (diphenhydramine) may help hives but not a rash which has lasted more than 24 hrs.
IM Benadryl (diphenhydramine) gives you perhaps a 30-minute head start vs oral = not worth the cost or hassle. If you have throat swelling , you may need adrenaline and an allergy consult since this can be life-threatening.

In brief: Depends

Benadryl (diphenhydramine) may help hives but not a rash which has lasted more than 24 hrs.
IM Benadryl (diphenhydramine) gives you perhaps a 30-minute head start vs oral = not worth the cost or hassle. If you have throat swelling , you may need adrenaline and an allergy consult since this can be life-threatening.
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