77 year old's MRI - chronic microvascular ischemic disease & shrinking of brain. No diabetes or high BP. Hasn't smoked for 30 yrs. What's the cause?

Well that's the question. As we age the brain tends to lose fluid content. There are many seniors who do not have this issue while others do. The micro vascular ischemia is not dependent upon diabetes but small vessels that become blocked by many things including blood clots and cholesterol. Often times it doesn't affect the function of the individual. Occasionally it will.

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